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Welcome.
This is the homepage for Paul
Curnow. I am a Research
Associate in the School of Biochemistry at the University
of Bristol, UK, with interests
in the folding and
reconstitution of integral membrane proteins and the potential
application of these proteins in nanotechnology.
I am currently investigating the structure and function of silicon
transport proteins in vitro
with the eventual aim of exploiting the silicon binding and transport
properties of these proteins in bionanotechnology. This is supported by
funding from the BBSRC and an ERC Starting Grant.
Previously, I worked
with Professor Paula Booth
on the
reversible unfolding of the proton pump bacteriorhodopsin. Before that,
I was a postdoctoral Fellow at the University
of California, Santa Barbara
in the lab of Daniel Morse
where I used the outer membrane protein OmpA as a scaffold for
cell surface display of a biomineralizing enzyme. My PhD studies, also
at Bristol, concerned the
reconstitution of the multidrug transporter EmrE.
I was awarded the 2009 Early
Career Research Award in
Bioenergetics and Metabolism from the Biochemical
Society.
Recent publications can be found here,
and a more detailed research synopsis here.
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